Surgery for Thyroid Eye Disease

One or more surgeries can help repair several changes caused by Thyroid Eye Disease (TED). Surgery for TED may help correct bulging eyes, double vision, pulled-back eyelids, misaligned eyes, and other changes to appearance and vision. Usually multiple surgeries are needed. Below are some of the types of surgeries for TED:

Orbital decompression surgery: helps reduce bulging eyes
Strabismus surgery: helps correct eyes that aren’t properly aligned or point in different directions (also called strabismus) and double vision
Eyelid repositioning surgery: helps repair eyelid changes, like pulled-back eyelids (also called eyelid retraction)
Facial surgery: helps address other changes to the eyes and face caused by TED

Orbital decompression surgery for Thyroid Eye Disease

In orbital decompression surgery, the surgeon will remove, shave, or sculpt a section of bone from behind the eye to help the eye move back into its socket. The surgeon may also remove some fat from behind the eye, and room is made behind the eye for the enlarged muscles that developed with the disease. Orbital decompression may be done endoscopically, meaning a small cut is made above the eye or through the nose.

Strabismus surgery for Thyroid Eye Disease

To help correct double vision and/or misaligned eyes, strabismus surgery may be needed. During this surgery, the surgeon moves the muscles around the eye to get the eyes to point in the same direction. In about 25% of cases, more than 1 surgery is needed to achieve good muscle placement.

Eyelid repositioning surgery for Thyroid Eye Disease

Eyelid repositioning surgery will help correct retracted (pulled-back) eyelids, which can also help reduce dryness. During eyelid repositioning surgery, the surgeon releases the muscles and tendons around the eyelid, allowing the lid to return to a more natural position. One common phrase associated with this surgery is that the “eyelids are lengthened.”

Facial surgery for Thyroid Eye Disease

To restore the appearance of the eyes and face, facial surgery may be necessary. The swollen and puffy tissue around the eye can be treated with face sculpting surgery such as blepharoplasty (also called an eye lift, or facelift surgery). The aged appearance of the skin can be treated with laser resurfacing and injections.

Learn how Kim saw results with TEPEZZA when other options failed

Kim had several surgeries for Thyroid Eye Disease. When it flared again, her doctor recommended TEPEZZA.

Watch Kim’s TEPEZZA results story

USE and IMPORTANT SAFETY INFORMATION

What is the most important information I should know about TEPEZZA?

Infusion reactions can happen during or within 24 hours after your infusion of TEPEZZA. If you have a reaction while receiving TEPEZZA, your doctor or nurse will slow or stop your infusion and treat your reaction. If you have a severe infusion reaction, your doctor may stop your treatment completely.

Tell your doctor or nurse right away if you have any of these symptoms during or after your treatment with TEPEZZA:

High blood pressure
Fast heartbeat
Redness of the face/Feeling hot

Difficulty breathing
Headache
Muscle pain

If you have inflammatory bowel disease (IBD), such as Crohn's disease or ulcerative colitis, TEPEZZA may make your IBD symptoms worse. Symptoms of worsening IBD may include: an increased number of loose stools with stomach pain or cramps, and blood in your stools. After each TEPEZZA infusion, tell your doctor right away if you have worsening IBD symptoms.

TEPEZZA may cause an increase in your blood sugar. Before starting treatment with TEPEZZA, tell your doctor if you are currently being treated for diabetes, know your blood sugar is high, or have been diagnosed with diabetes. It is important for you to take your treatments and follow an appropriate diet for glucose control as prescribed by your doctor.

TEPEZZA may cause severe hearing problems including hearing loss, which in some cases may be permanent. Tell your doctor if you have any signs or symptoms of hearing problems or changes in hearing.

Before receiving TEPEZZA, tell your doctor if you:

Have inflammatory bowel disease (Crohn's disease or ulcerative colitis).
Are currently being treated for diabetes, have been diagnosed with diabetes, or know your blood sugar is high.
Are pregnant or plan to become pregnant. TEPEZZA may harm your unborn baby. Tell your doctor if you become pregnant or suspect you are pregnant during treatment with TEPEZZA.
- Women who are able to become pregnant should use an effective form of birth control (contraception) prior to starting treatment, during treatment and for at least 6 months after the final dose of TEPEZZA.
Are breastfeeding or plan to breastfeed. It is not known if TEPEZZA passes into your breast milk. Talk to your doctor about the best ways to feed your baby during treatment with TEPEZZA.
Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, dietary and herbal supplements. Know the medicines you take. Keep a list of them to show your doctor and pharmacist when you get a new medicine.

What are the possible side effects of TEPEZZA?

The most common side effects of TEPEZZA include muscle cramps or spasms, nausea, hair loss, diarrhea, feeling tired, high blood sugar, hearing problems, taste changes, headache, dry skin, weight loss, nail problems, and changes in menstruation.

This is not a complete list of all possible side effects. Tell your doctor or treatment team about any side effect you may have.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/safety/medwatch, or call 1-800-FDA-1088.

Please visit TEPEZZA.com for more information.

USE

TEPEZZA is a prescription medicine used to treat Thyroid Eye Disease (TED), no matter if you’ve had TED for months or years.

P-TEP-US-00841-3 07/23