Please ensure JavaScript is enabled for purposes of website accessibility Continuing Your Treatment | TEPEZZA® (teprotumumab-trbw)

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*For eligible commercial patients. Terms and conditions apply.

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Continuing Your TEPEZZA Treatment

To make the most of treatment with TEPEZZA, it’s recommended that you get all 8 infusions

In clinical studies, patients started to see improvements in eye bulging at different times, but many saw the best results after completing 8 infusions:

*Patients A and B are real patients treated with TEPEZZA in a clinical study. Individual results may vary. 8 out of 10 patients had at least 2 mm improvement in one eye without worsening in the other.

Based on the results from the clinical studies, the improvements seen in patients who completed all 8 infusions included:

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What to expect after each infusion

Your infusion nurse or another member of your infusion team will monitor you for a short time after each infusion to make sure you do not have a reaction to the medicine. Every infusion center is different. Check with your infusion center about how they prefer to do this.

Stay on track by being prepared

After the monitoring is over, taking care of a few things can help make sure your next appointment goes smoothly and you stay on track to complete your treatment.

  • Schedule your next infusion and check out
  • Confirm your transportation home
  • Complete the After Infusion Reminder List so you know you have the details covered for your next appointment

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  • Do something special for yourself afterwards. You’re taking care of your Thyroid Eye Disease (TED), so you deserve it!
  • Use this Treatment Progress Tracker to note any changes to how you look and feel in between infusion appointments

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  • Make sure you’re ready for your next TEPEZZA infusion with this checklist

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  • Remember to trust the process. It’s normal to be anxious to start seeing changes in your TED symptoms. Staying on track with your treatment plan as prescribed by your doctor will allow you to get the full benefits of treatment. Take a look at the graph above to see when patients in clinical studies started to see results.
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After my 8th infusion, my eye bulging had gone down 5 mm and I had no double vision. I couldn’t have been happier.”

– Karen W., real TEPEZZA patient

Disease flare-ups

It is not common to have symptoms return after treatment with TEPEZZA. But if this happens, another course of TEPEZZA treatment may help.

Even with treatment, people with autoimmune disorders may experience flare-ups later. Approximately 15% of TED patients may experience a return of symptoms (or “flare”), regardless of how their TED was originally treated. If your TED symptoms return, talk to your doctor about the possibility of another course of treatment.

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P-TEP-US-01353 10/23

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USE and IMPORTANT SAFETY INFORMATION

What is the most important information I should know about TEPEZZA?

Infusion reactions can happen during or within 24 hours after your infusion of TEPEZZA. If you have a reaction while receiving TEPEZZA, your doctor or nurse will slow or stop your infusion and treat your reaction. If you have a severe infusion reaction, your doctor may stop your treatment completely.

Tell your doctor or nurse right away if you have any of these symptoms during or after your treatment with TEPEZZA:
  • High blood pressure
  • Fast heartbeat
  • Redness of the face/Feeling hot
  • Difficulty breathing
  • Headache
  • Muscle pain

If you have inflammatory bowel disease (IBD), such as Crohn's disease or ulcerative colitis, TEPEZZA may make your IBD symptoms worse. Symptoms of worsening IBD may include: an increased number of loose stools with stomach pain or cramps, and blood in your stools. After each TEPEZZA infusion, tell your doctor right away if you have worsening IBD symptoms.

TEPEZZA may cause an increase in your blood sugar. Before starting treatment with TEPEZZA, tell your doctor if you are currently being treated for diabetes, know your blood sugar is high, or have been diagnosed with diabetes. It is important for you to take your treatments and follow an appropriate diet for glucose control as prescribed by your doctor.

TEPEZZA may cause severe hearing problems including hearing loss, which in some cases may be permanent. Tell your doctor if you have any signs or symptoms of hearing problems or changes in hearing.

Before receiving TEPEZZA, tell your doctor if you:
  • Have inflammatory bowel disease (Crohn's disease or ulcerative colitis).
  • Are currently being treated for diabetes, have been diagnosed with diabetes, or know your blood sugar is high.
  • Are pregnant or plan to become pregnant. TEPEZZA may harm your unborn baby. Tell your doctor if you become pregnant or suspect you are pregnant during treatment with TEPEZZA.
    • Women who are able to become pregnant should use an effective form of birth control (contraception) prior to starting treatment, during treatment and for at least 6 months after the final dose of TEPEZZA.
  • Are breastfeeding or plan to breastfeed. It is not known if TEPEZZA passes into your breast milk. Talk to your doctor about the best ways to feed your baby during treatment with TEPEZZA.
  • Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, dietary and herbal supplements. Know the medicines you take. Keep a list of them to show your doctor and pharmacist when you get a new medicine.
What are the possible side effects of TEPEZZA?

The most common side effects of TEPEZZA include muscle cramps or spasms, nausea, hair loss, diarrhea, feeling tired, high blood sugar, hearing problems, taste changes, headache, dry skin, weight loss, nail problems, and changes in menstruation.

This is not a complete list of all possible side effects. Tell your doctor or treatment team about any side effect you may have.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/safety/medwatch, or call 1-800-FDA-1088.
Please visit TEPEZZA.com for more information.

USE

TEPEZZA is a prescription medicine used to treat Thyroid Eye Disease (TED), no matter if you’ve had TED for months or years.

P-TEP-US-00841-3 02/25

USE and IMPORTANT SAFETY INFORMATION